Amplified in breast cancer 3 gene in tumors
10.3760/cma.j.issn.1673-422X.2012.10.001
- VernacularTitle:乳腺癌扩增基因3在肿瘤中的研究
- Author:
Lei BI
;
Hao ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Nuclear receptor coactivator;
Cell proliferation
- From:
Journal of International Oncology
2012;39(10):723-725
- CountryChina
- Language:Chinese
-
Abstract:
Amplified in breast cancer 3 (AIB3) is a newly discovered pleiotropic nuclear receptor co-activator.AIB3 regulates cell proliferation,growth,migration and apoptosis by interacting with many nuclear receptors.At the mean time,some reports show that AIB3 interacts with variety of transcription factors,which indicates AIB3 may play an important role in cancer occurrence and progression.
