Circulating Lymphoma Cells in the Peripheral Blood from 4 Cases of Mantle and T Cell Types of Non-Hodgkin's Lymphoma: Light and Electron Microscopic Morphology.
- Author:
Ha Young CHOI
1
;
Gun PARK
;
Seung Min HONG
;
Sook Jin JANG
;
Dae Soo MOON
;
Young Jin PARK
Author Information
1. Department of Clinical Pathology, College of Medicine, Chosun University, Kwangju, Korea
- Publication Type:Original Article
- Keywords:
T cell;
Lymphocyte;
Leukemia;
Lymphoma
- MeSH:
Adult;
Biopsy;
Humans;
Incidence;
Leukemia;
Lymph Nodes;
Lymphocytes;
Lymphoma*;
Lymphoma, Mantle-Cell;
Lymphoma, Non-Hodgkin*;
Lymphoma, T-Cell, Cutaneous;
Lymphoma, T-Cell, Peripheral;
Monocytes
- From:Korean Journal of Clinical Pathology
1999;19(4):381-388
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is difficult to distinguish between circulating lymphoma cells and non-lymphoma cells which are lymphocytes, activated lymphocytes, monocytes, and leukemic cells. The presence of circulating lymphoma cells in the peripheral blood is infrequent but the incidence is probably significantly higher than has been reported in morphologic studies of peripheral blood smears. So the morphologic evaluations of the circulating lymphoma cells and non-lymphoma cells are needed. We experienced that circulating lymphoma cells were found in the peripheral blood smears in the 4 cases of non-Hodgkin's lymphomas. They were consisted of mantle cell lymphoma (1 case), peripheral T cell lymphoma (1 case), adult T cell leukemia/lymphoma (1 case), cutaneous T cell lymphoma (1 case) and diagnosed from their lymph node biopsies. Those circulating lymphoma cells were morphologically observed by light and electron microscopic methods. Using those morphological features, we think that detection rate of circulating lymphoma cells can be improved in the patient with lymphoma.
