Matrix metalloproteinase-9 in the invasion and metastasis of colorectal cancer
10.3760/cma.j.issn.1673-422X.2012.10.016
- VernacularTitle:基质金属蛋白酶-9对结直肠癌侵袭转移的影响
- Author:
Xingzhu CHEN
;
Lihong ZHOU
;
Qi LI
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinases-9;
Colorectal neoplasms;
Neoplasm invasiveness;
Neoplasm metastasis
- From:
Journal of International Oncology
2012;39(10):772-775
- CountryChina
- Language:Chinese
-
Abstract:
Matrix metalloproteinases-9(MMP-9) is an important gene in coloreetal cancer occurrence and development.MMP-9 can induce cell proliferation,angiogenesis and neoplasm infiltration,and then leads to coloreetal cancer invasion and metastasis.MMP-9 can not only play the role individually in coloreetal canccr invasion and migration,but also can cooperate with other genes.MMP-9 is a key protease in terminal metastasis of coloreetal cancer.
