Hormone replacement therapy for gynaecological cancer
10.3760/cma.j.issn.1673-422X.2012.10.018
- VernacularTitle:妇科肿瘤患者的激素替代治疗
- Author:
Yichen WANG
;
Xiaoxian XU
;
Yanmin SHEN
;
Aijun YU
- Publication Type:Journal Article
- Keywords:
Hormone replacement therapy;
Menopause;
Genital neoplasms,female
- From:
Journal of International Oncology
2012;39(10):778-781
- CountryChina
- Language:Chinese
-
Abstract:
Treatment of gynaeeological cancer frequently results in the loss of ovarian function and menopausal syndrome.The most effective treatment is hormone replacement therapy (HRT).According to the current studies,HRT does not increase the risk of recurrence or death in patients with early stage endometrial cancer and uterine leiomyosarcomas. The safety of HRT in ovarian cancer patients is inconclusive. Cervical squamous cell carcinoma, vaginal cancer and vulvar cancer are not contraindications for HRT. Estrogen replacement therapy (ERT) is contraindicated for low-grade endometrial stromal sarcomas. Therefore,after integrated risk assessment and discussion,patients with severe menopausal symptoms can be treated with HRT to improve the quality of life.