Nursing of patients with type 2 diabetes mellitus using exenatide targets site treatment
10.3760/cma.j.issn.1672-7088.2012.25.004
- VernacularTitle:艾塞那肽靶点治疗2型糖尿病患者的护理干预
- Author:
Qun LU
;
Xiaojuan YAO
;
Haifeng SUN
;
Jing TAN
;
Ying WU
;
Rong CAO
;
Mingzhu CHEN
;
Yi JIN
- Publication Type:Journal Article
- Keywords:
Nursing intervention;
Exenatide;
Target treatment;
Type 2 diabetes
- From:
Chinese Journal of Practical Nursing
2012;28(25):7-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore exenatide in the treatment of metformin(MET)alone,sulfonylurea (SU)alone or MET + SU combination therapy with poor glycemic control in type 2 diabetic pa-tients and to find effective nursing measures.Methods 24 patients were randomly divided into the con-trol group and the exenatide group with 12 patients in each group.In the exenatide group,exenatide 5μg twice a day for 4weeks,then 10μg twice a day for 12 weeks.Changes of HbAlc,body weight,BMI,FBG,P2hBG,and rate of adverse reaction were compared between two groups.Results Glycosylated hemoglobin (HbAlc),body weight,BMI,FBG,P2hBG in the control group before and after treatment showed no significant difference,while the exenatide group showed better results compared with those before treatment and the control group.Nursing intervention played evident effect on reducing adverse effect such as nausea,vomiting,diarrhea,low blood sugar,headache.Conclusions For patients with type 2 diabetes,using MET,SU alone or MET + SU combination therapy showed poor results of blood sugar control,addition of exenatide therapy can effectively control blood sugar,nursing intervention can significantly alleviate the adverse effects of patients.
