Value of virtual touch tissue quantification technique in the diagnosis of small solid thyroid nodules
10.3760/cma.j.issn.1004-4477.2012.09.012
- VernacularTitle:声触诊组织量化技术对甲状腺实性小结节良恶性的鉴别诊断价值
- Author:
Lili XIAO
;
Yaping ZHAO
;
Lingyun GAO
;
Haiyan ZHANG
;
Bing YE
;
Ximing Lü
;
Chongyong XU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid neoplasms;
Virtual touch tissue quantification
- From:
Chinese Journal of Ultrasonography
2012;21(9):771-774
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of virtual touch tissue quantification(VTQ) technique in differentiating small solid thyroid nodules.Methods The patients with suspiciously malignant thyroid nodules(solitary,size range 5-15 mm),homogeneous and normal color Doppler flow imaging in the rest of thyroid parenchyma,were enrolled in this study.Five repeated measurements were performed on both nodules and extra-nodular tissues using VTQ.A receiver-operating characteristic (ROC) curve was drew according to shear wave velocity(Vs).Results 62 patients with a total of 67 lesions were included in this study,turned out to be 39 malignant and 28 benign.The Vs of malignant group nodules,malignant group extra-nodular tissues,benign group nodules and benign group extra-nodular tissues were (3.91 ±1.85) m/s,(2.03 ± 0.42)m/s,(2.29 ± 0.56)m/s,(1.84 ± 0.45)m/s,respectively.The Vs difference between malignant and benign nodules was statistically significant (P =0.000),while the Vs difference between malignant and benign extra-nodular tissues had no statistical significance (P =0.07).The best cutoff Vs value for distinguishing malignant from benign nodules was 2.78 m/s,with the sensitivity,specificity and accuracy of 76.9％,78.6％ and 80.6％ respectively.The area under ROC curve was 0.84.Conclusions VTQ could evaluate the elasticity of thyroid nodules,and was helpful in the diagnostic work-up of thyroid nodules.
