Prediction of D-dimer levels on the clinical stage and pathological grade of patients with ovarian cancer

VernacularTitle:D-二聚体水平对卵巢癌患者临床分期及病理分级的预测作用
Author: Rui CUI ; Peiling LI ; Lingdi WANG ; Lei FANG ; Xin MA ; Yuyan ZHANG
Publication Type:Journal Article
Keywords: Ovarian neoplasms; D-dimer; Clinical stage; Pathological grade
From: Chinese Journal of Postgraduates of Medicine 2012;35(27):18-19
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship between D-dimer levels and the clinical stage and pathological grade of patients with ovarian cancer.Methods The clinical data of 66 patients with ovarian cancer whose D-dimer had been monitored before surgery were retrospectively analyzed.The relationship between D-dimer levels and the clinical stage,pathological grade was evaluated.Results D-dimer levels before surgery were uncorrelated with the patient's age (r =0.1324,P ＞ 0.05 ).There was significant difference in D-dimer levels between FIGO Ⅰ + Ⅱ patients and FIGO Ⅲ + Ⅳ patients [(377.89 ± 183.85) mg/L vs.(858.03 ± 138.29) mg/L] (t =11.602,P＜0.01).There was significant difference in D-dimer levels between high-moderately differentiated patients and poorly differentiated patients [(463.39 ±246.85) mg/L vs.(784.64 ±265.69) mg/L](t =4.983,P＜0.01).Conclusions D-dimer levels are related with the clinical stage and pathological grade of patients with ovarian cancer.It can predict the harmful biological behaviour of ovarian cancer.