mTOR in gastric cancer
10.3760/cma.j.issn.1673-422X.2012.09.015
- VernacularTitle:mTOR与胃癌
- Author:
Li XIN
;
Qingcai WANG
- Publication Type:Journal Article
- Keywords:
Mammals;
Protein kinase inhibitors;
Stomach neoplasms
- From:
Journal of International Oncology
2012;39(9):690-693
- CountryChina
- Language:Chinese
-
Abstract:
Mammalian target of rapamycin (mTOR) is an atypical serine / threonine protein kinase,and belongs to the phosphatidylinositol kinase-related kinase (PIKK) family.mTOR plays an important role in tumor cell growth,apoptosis and tumor angiogenesis. Molecular therapy targeted mTOR has become a hot research topiccurrently.
