The analysis of the effect of transsphenoidal microsurgical operation in patients with prolatinomas

VernacularTitle:经鼻蝶窦切除垂体生长激素腺瘤疗效分析
Author: Zhimin HUANG ; Hongchuan LONG ; Anzhi LUO ; Yun WU ; Zongyin ZHANG ; Hualin YU
Publication Type:Journal Article
Keywords: Somatotropinoma; Operation; Effects
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(20):3043-3044
CountryChina
Language:Chinese
Abstract: ObjectiveTo assess the recent effect of the invasiveness and transsphenoidal microsurgical operation in the treatment of growth hormone-secreting adenom tumor.MethodsThe data of 22 patients with growth hormone(GH) adenomas were collected.All patients were tested preoperative GH level and that within the first 3 days,30 days following surgery.The invasiveness of pituitary adenomas was judged according to Hardy's classification scheme modified by Wilson.ResultsThere were 22 patients with GH-secreting pituitary adenomas,8 males and 14 females,11 patients with invasive adenomas and 11 patients with noninvasive adenomas.The remission rate between the patients with invasive adenomas and the patients with non-invasive adenomas had no statistically significant difference (P ＞ 0.05 ).The postoperative remission rate of patients with GH values ≤ 50μg/L was no significantly lower than that of ＞ 50μg/L( P ＞ 0.05).ConclusionThe recent effects of operation were not significantly different with the invasiveness of tumor.