Upper-gastrointestinal polyps found in cases of familial adenomatous polyposis

VernacularTitle:家族性腺瘤性息肉病伴发上消化道息肉57例分析
Author: Xiaodong XU ; Chuangang FU ; Ning SONG ; Wei ZHANG ; Lianjie LIU ; Ronggui MENG ; Enda YU
Publication Type:Journal Article
Keywords: Adenomatous polyposis coli; Polyps; Pathology,clinical
From: Chinese Journal of General Surgery 2012;27(8):613-615
CountryChina
Language:Chinese
Abstract: ObjectiveTo discuss the incidence,endoscopic manifestion and pathological features of the upper-gastrointestinal polyps ( stomach and deodenum) in FAP patients. MethodsDuring 2004 -2010 a total 57 FAP patients at Changhai Hospital underwent screening for polyps in upper-gastrointestinal tract by gastroscopy and sideward-viewing duodenoscopy. Biopsies were taken on the polypoid lesions.ResultsGastric polyps were found in 38 patients (67％).Most polyps were located at gastric body and antrum,the pathologic diagnosis was hyperplastic. Duodenal polyps were found in 12 patients (21％) including 7 cases of adenomatous polys. ConclusionsUpper- gastrointestinal polyps are the most common extra-colonic manifestion in FAP. Most stomach polyps are located at gastric body and antrum and are hyperplastic.Polyps at duodenum may be adenomatous,which is a precusor of carcinoma.