Clinical experience in 36 cases of T4 esophageal carcinoma radical surgery combined with descending thoracic aortic segment replacement
10.3760/cma.j.issn.1008-6315.2012.10.027
- VernacularTitle:联合胸降主动脉节段置换的T4期食管癌根治术36例临床分析
- Author:
Guohua DONG
;
Hua JING
;
Demin LI
;
Zhongdong LI
;
Biao XU
;
Yi SHEN
;
Sheng YAO
;
Canhui LIU
;
Haiwei WU
- Publication Type:Journal Article
- Keywords:
Esophagus carcinoma;
Aorta replacement;
Thoracic descending aorta
- From:
Clinical Medicine of China
2012;28(10):1090-1093
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summary the experience of T4 esophageal carcinoma surgery and to explore the methods and operating skills on descending thoracic aortic resection with prosthetic vascular graft replacement in patients with T4 locally advanced esophageal carcinoma invading descending thoracic aorta.Methods From Jan.2001 to Dec.2010,36 patients with esophageal carcinoma underwent esophagectomy and descending aortic replacement simultaneously in our hospital.The clinical data were retrospectively reviewed.All patients had a left posterior lateral incision via the 6th intercostal space.The vascular adventitia of the descending thoracic aorta in the left side was incised,and the aorta was clamped in the proximal and distal side of the invaded segment.Then the invaded segment was resected and replaced with artificial vessels.Esophageal carcinoma was radically resceted,and left cervical esophageal-gastro anastomosis was performed in all patients.Results Radical resection of esophageal carcinoma was achieved in all patients.There was no perioperative death,or severe complications such as paraplegina,acute renal failure and intestinal dysfunction occurred.Two patients had chylous hydrothorax,and one had late stage anastomotic stoma fistula.The post-operative hospital stay was 10-42 d,mean (15.5 ± 7.2 )d.The pathological examination revealed that all the patients had squamous cell carcinoma.The aortic tunica adventitia was invaded in all the patients,9(25% ) had tunica media invasion,and there was no tunica intima invasion observed.The 1-,3-,and 5-year survival rate was 80.6%,46.2% and 20.0% respectively.Conclusion Combined esophagectomy and descending aortic replacement for locally advanced T4 esophageal carcinoma invading aorta can be considered as radical operation for selected patients,and it can improve the survival rate and life quality of the patients.