CXCL12/CXCR4 and breast cancer
10.3760/cma.j.issn.1673-422X.2012.09.013
- VernacularTitle:趋化因子CXCL12及其受体CXCR4与乳腺癌
- Author:
Shuangfei XU
;
Zhigang ZHUANG
- Publication Type:Journal Article
- Keywords:
Chemokine CXCL12;
CXCR4 Receptor;
Breast neoplasms
- From:
Journal of International Oncology
2012;39(9):683-686
- CountryChina
- Language:Chinese
-
Abstract:
CXCL12 and its receptor CXCR4 can express in breast cancer,and are regulated by several factors in the genesis and development of breast cancer. Lots of researches have proved that CXCL12 and CXCR4 can be used as new independent prognostic makers of breast cancer.Treatment targeted for CXCR4 can be seen as a new kind of combination therapy,which may provides patients a more ideal treatment.