Toll-like receptor in children's rotavirus infection
10.3760/cma.j.issn.1673-4408.2012.05.003
- VernacularTitle:Toll样受体在小儿轮状病毒感染中的研究进展
- Author:
Haiyan YANG
- Publication Type:Journal Article
- Keywords:
Toll-like receptor;
Rotavirus;
Signal conduct;
Natural immune;
Required immune
- From:
International Journal of Pediatrics
2012;39(5):441-444
- CountryChina
- Language:Chinese
-
Abstract:
Toll-like receptor is a receptor to identify the pathogen associated molecular,which relates the natural immune with required immune.Toll-like receptor activates natural immune and induces several cytokines.As a result,it will influence the differentiation of initiated T-cell by identifying Pathogens.The main Tolllike including TLR2、3、4、7、8、9 are closely related with anti-rotavirus to identify the natural immune affection of rotavirus.This review to explain the pathogenesis of Toll-like in rotavirus infection,as well as the key role which Toll-like plays in preventing rotavirus infection and controlling the inflammation.
