Research progress on anti-tumor and immunity activity of CpG
10.3760/cma.j.issn.1673-422X.2012.09.009
- VernacularTitle:CpG抗肿瘤作用及其免疫活性的研究进展
- Author:
Zhenghai TANG
;
Xiaowen WANG
;
Jingtian TANG
- Publication Type:Journal Article
- Keywords:
CpG;
immunoactivity;
Neoplasms
- From:
Journal of International Oncology
2012;39(9):671-674
- CountryChina
- Language:Chinese
-
Abstract:
CpG motifs are unmethylated oligodeoxynucleotides,and its core sequences are composed of unmethylated cytosine and unmethylated guanine.CpG motifs can induce the immune response by activating a variety of immune cells against diseases.The changes of CpG structure will increase the biological activities of CpG,and then enhance the therapeutic effect of CpG as the immuno adjuvant and the sensitizer of radiotherapy and chemotherapy in cancer treatment
