Vitamin D and its receptor in the role of kidney disease
10.3760/cma.j.issn.1673-4408.2012.05.014
- VernacularTitle:维生素D及其受体在肾脏疾病中作用的研究进展
- Author:
Fujuan WANG
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Vitamin D receptor;
Kidney disease
- From:
International Journal of Pediatrics
2012;39(5):480-483
- CountryChina
- Language:Chinese
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Abstract:
Vitamin D is an important hormone.Its biological effect is mediated by intracellular vitamin D receptor-specific.In recent years,studies have shown that active vitamin D and its receptor can reduce the degree of the pathological changes of the glomerular and tubular interstitial fibrosis,decrease 24 hour urinary protein,reduce the mortality rate of cardiovascular diseases,and have protective effect on chronic kidney disease.This paper reviews progress of the vitamin D and its receptor in kidney disease.