The expression of AP-1 in pancreatic tumor cells
10.3760/cma.j.issn.1008-6706.2012.20.011
- VernacularTitle:AP-1在胰腺癌组织中的表达
- Author:
Xiaoyu SHEN
- Publication Type:Journal Article
- Keywords:
Genes,AP-1;
Pancreatic neoplasms
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(20):3060-3061
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the expression of AP-1 in pancreatic tumor cells and its clinical significance.MethodsSelected the paraffin-embedded specimens from the tumor tissues of 35 patients with pancreatic cancer(study group) and 35 pancreatic tissue of healthy people(control group),and double antibody sandwich ABCELISA detection of AP-1 was carried out,two sets of specimens C-JUN and C-FOS expression was observed.ResultsObservation group C-JUN and C-FOS expression positive rates were 80.00％ 71.43％,control group,C-JUN and C-FOS expression positive rates were 22.86％,28.57％,there was a significant difference between the two groups.ConclusionAP-1 was highly expressed in pancreatic cancer,which could guide clinical take reasonable interventions to slow tumor development.
