Study on the detection of serum β2-MG, RBP and Cys-C test for early diagnosis of acute kidney injury

VernacularTitle:血清β2-微球蛋白、视黄醇结合蛋白和胱抑素-C检测对急性肾损伤早期诊断的价值
Author: Fangcai ZHONG
Publication Type:Journal Article
Keywords: β2-microglobulin; Retinal binding protein; Cystatin C; Acute kidney injury(AKI)
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(20):3072-3073
CountryChina
Language:Chinese
Abstract: ObjectiveThrough different disease period the serum β2-microglobulin (β2-MG),Retinal binding protein (RBP) and Cystatin C (Cys-C) joint test,to evaluate the clinical value of the combination detection of early diagnosis of acute kidney injury (AKI).MethodsOur choice in March 2011 to February 2012 in the same period and 88 patients with AKI physical examination in 63 cases,in the new HITACHI7600-020 automatic biochemistry analyzer and into test sample β2-MG,RBP and Cys-C content.ResultsThe patients with AKI of serum β2-MG,RBP and Cys-C compared with the control were significantly increased,the differences were significant ( P ＜ 0.05 or P ＜0.01 ).ConclusionSerum β2-MG,RBP and Cys-C are sensitive idicators in early diagnosis of AKI,three united detection help early diagnosis AKI,clinical doctors can provide reliable accurate valuable diagnostic basis for guidance.