The relationship between preoperative plasma N-terminal pro-brain natriuretic peptide and recurrence of atrial fibrillation after cardiac valve replacement combined with radiofrequency ablation
10.3760/cma.j.issn.1673-4904.2012.26.004
- VernacularTitle:术前血浆N-末端脑钠肽前体浓度与瓣膜置换同期射频消融术后心房颤动复发的关系
- Author:
Wei SUN
;
Bing SONG
;
Dianwei CHENG
;
Debin LIU
- Publication Type:Journal Article
- Keywords:
Heart valve prosthesis implantation;
Catheter ablation;
Atrial fibrillation;
N-terminal pro-brain natriuretic peptide
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(26):11-13
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between preoperative plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) and recurrence of atrial fibrillation (AF) after cardiac valve replacement (CVR) combined with radiofrequency ablation.Methods Fifty-eight patients with AF undergoing CVR combined with radiofrequency modified Maze procedure were enrolled in this study.The patients were allocated to either AF recurrence group (AF group,18 cases) or AF no recurrence group (SR group,40 cases) according to whether patient's AF recurrence or not within 3 months after surgery.NT-proBNP were respectively measured in two groups in 1st day before operation and 9th day after operation by radioimmunoassay.Results All the 58 patients were involved in the final analysis.NT-proBNP levels in 1st day before operation and 9th day after operation in AF group was significantly higher than that in SR group (2061.30 ng/L vs.579.00 ng/L,996.60 ng/L vs.209.20 ng/L,P＜ 0.01 ).NT-proBNP levels in 1st day before operation in two groups was significantly higher than that in 9th day after operation (P ＜ 0.01 ).Conclusions There is a good relationship between preoperative plasma NT-proBNP levels and recurrence of AF.It has a clinical value in predicting of recurrence AF after CVR combined with radiofrequency modified Maze procedure.
