Meta-analysis on the efficacy and safety of Danhong injection in the treatment of cerebral infarction
10.3760/cma.j.issn.1671-7368.2012.05.023
- VernacularTitle:丹红注射液治疗脑梗死临床疗效和安全性的Meta分析
- Author:
Yang YANG
;
Lingxia ZENG
- Publication Type:Journal Article
- Keywords:
Cerebrovascular disorders;
Meta-analysis
- From:
Chinese Journal of General Practitioners
2012;11(5):372-375
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the clinical efficacy and safety of Danhong injection in the treatment of cerebral infarction.A total of 27 randomized controlled trials were retrieved from the literature and analyzed by Meta-analysis with RevMan 5.0 software.All were at level B or above after quality assessment.The clinical efficacy of Danhong injection was better than that of the control group in the treatment of cerebral infarction( RR =1.21,95％ CI:1.17 - 1.26 ).After the administration of Danhong injection,the score of National Institute of Neurological Disorders and Stroke (NIHSS) and hemorrheologic indices were significantly lower than those of the control group (P ＜0.01 ).There was no obvious adverse reaction.The clinical efficacy and safety of Danhong injection have marked advantages over Danshen and Fufang Dansheng injection in the treatment of cerebral infarction.
