Values of fractional exhaled nitric oxide plus serum procalcitonin and C-reactive protein in the evaluation of asthma
10.3760/cma.j.issn.1671-7368.2012.05.025
- VernacularTitle:呼出气一氧化氮联合降钙素原和C反应蛋白在哮喘诊治中的价值
- Author:
Limin ZHAO
;
Lijun MA
;
Jizhen WU
;
Xianliang CHEN
;
Hongyan NIU
- Publication Type:Journal Article
- Keywords:
Asthma;
Bacterial infections;
Diagnostic techniques and procedures
- From:
Chinese Journal of General Practitioners
2012;11(5):377-378
- CountryChina
- Language:Chinese
-
Abstract:
A total of 60 patients with an acute attack of asthma were studied.On presentation,fractional exhaled nitric oxide (FeNO) and the serum concentrations of procalcitonin (PCT) and C-reactive protein (CRP) were measured.And sputum culture was also performed.The patients were re-evaluated while returning to their clinical remission states.They were classified into 2 groups:patients with bacterial infection (group A) and those with nonbacterial infection (group B).The levels of FeNO were significantly higher in patients with acute exacerbation than those in remission.No difference existed between groups A and B ( P ＞ 0.05 ).The levels of PCT and CRP of group A with acute exacerbation were significantly higher than those of group B( all P ＜0.05).While in remission,the levels of PCT and CRP decreased significantly in group A ( P ＜ 0.05 ) ; But compared with exacerbation,the levels of PCT and CRP showed no change in group B (P ＞0.05).And no differences existed between two groups while in remission (P ＞ 0.05 ).An elevation of FeNO indicates the acute exacerbation of asthma.And the increased serum levels of PCT and CRP are associated with bacterial infection.
