Influence factors on prognosis of the patients with capillary leak syndrome
10.3760/cma.j.issn.1671-0282.2012.03.017
- VernacularTitle:影响毛细血管渗漏综合征预后的因素分析
- Author:
Jun SU
;
Jinquan WANG
;
Xiaogen TAO
;
Bao LIU
;
Baoding MO
;
Lin ZHANG
- Publication Type:Journal Article
- Keywords:
Capillary leak syndrome;
Prognosis;
Influence factors;
Intensive Care Unit (ICU)
- From:
Chinese Journal of Emergency Medicine
2012;21(3):290-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss influence factors on prognosis of the patients with capillary leak syndrome (CLS) in ICU.Methods The clinical data of 191 patients with CLS in ICU were reviewed,and the patients were divided into three groups according to prognosis:death group ( n =37),cured group ( n =132) and non-healed group (n =22).The clinical data of death group were compared with those of cured group at admission,during the course of CLS and before discharging from hospital.Results Compared with the cured group,the central venous pressure and serum albumin decreased ( P ＜ 0.01 ) ; anion gap,triglycerides,pressure adjusted heart rate (PAHR) and oxygenation index were lower ( P ＜ 0.01 or P ＜ 0.05) ; serum glucose and SIRS score increased ( P ＜ 0.01 ) in death group.There was higher rate of poor renal function at admission in death group than that in other groups ( P ＜ 0.01 ).There were more many patients treated with intravenous administration of hydroxyethyl starch,ulinastatin and continuous blood filtration therapy in cured group than those in other groups ( P ＜ 0.05).Conclusions The factors influencing the outcomes of the patients with CLS were hypovolemia,severe hypoproteinemia,interior milieu disorder,malnutrition,hypoxemia,renal injury and severe systemic inflammatory response.The outcomes of patients with CLS in ICU could be improved by using hydroxyethyl starch,ulinastatin and continuous blood filtration therapy.
