Survival analysis for 131 patients with non-small cell lung cancer after resection
10.3760/cma.j.issn.1673-4904.2012.10.008
- VernacularTitle:131例非小细胞肺癌患者术后生存分析
- Author:
Weijun LIANG
;
Chengping HU
;
Min SONG
;
Qihua GU
;
Hongmei CHEN
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Prognosis;
Antineoplastic combined chemotherapy protocols;
Survival analysis
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(10):20-22
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the prognostic factors of non-small cell lung cancer (NSCLC) after resection.MethodsClinical data of 131 NSCLC patients who underwent resection were reviewed and divided into chemotherapy group(86 cases) and non-chemotherapy group(45 cases) according to the treatment method.Survival rate was calculated by Kaplan-Meier method.The prognosis was analyzed by Cox proportional hazards model.ResultsThe median survival time (MST) of squamous cell carcinoma (76 cases),bronchial alveolar cell carcinoma( 8 cases),adenocarcinoma( 35 cases ),adenosquamous carcinoma (12 cases) was 60,54,34,24 months respectively (P＜0.05).For the patients of stage Ⅰ B,the MST of chemotherapy group and non-chemotherapy group was 75 and 76 months respectively(P ＞ 0.05 ).Multivariate analysis showed that tumor size,T stage,N stage,chemotherapy were independent prognostic factors (P =0.080,0.002,0.000,0.029).Conclusions Squamous cell carcinoma and bronchial alveolar cell carcinoma have better prognosis than adenocarcinoma,adenosquamous carcinoma.For the patients of stage Ⅰ B,the survival time can't be prolonged through platinum-based chemotherapy.Tumor size,T stage,N stage,chemotherapy are independent prognostic factors.
