Remifentanil and etomidate target controlled infusion anesthesia in operation for esophageal cancer
10.3760/cma.j.issn.1673-4904.2012.09.008
- VernacularTitle:雷米芬太尼联合依托咪酯靶控输注麻醉用于食管癌手术
- Author:
Xiaobo XU
- Publication Type:Journal Article
- Keywords:
Etomidate;
Esophageal neoplasms;
Surgical procedures,operative;
Remifentanil;
Target controlled infusion anesthesia
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(9):21-23
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the application of remifentanil and etomidate target controlled infusion anesthesia in operation for esophageal cancer and observe its effects on hemodynamics.Methods Sixty patients of esophageal cancer were divided into control group and observation group by random digits table with 30 cases each.The observation group was given remifentanil and etomidate for induction of the general anesthesia,while the control group was given remifentanil and propofol.The changes of mean arterial pressure(MAP),heart rate(HR),postoperative spontaneous breathing recovery time,waking time,extubation time were observed.ResultsMAP after induction was lower than that lying for 10 minutes after entering operating room in two groups (P ＜ 0.05),and observation group was lower than control group (P ＜ 0.05).MAP,HR after 5 minutes extubation were higher than those lying for 10 minutes after entering operating room(P ＜ 0.05 ),and observation group was higher than control group (P ＜ 0.05 ).The postoperative spontaneous breathing recovery time,waking time,extubation time in observation group [ (5.3 ± 1.5 ),(6.4 ± 2.1 ),(8.4 ± 2.5 ) min ] were shorter than those in control group [ ( 16.9 ± 8.7 ),(21.3 ± 7.7),(23.7 ± 5.8)min],and there were significant differences (P ＜0.05).ConclusionRemifentanil and etomidate target controlled infusion anesthesia in operation for esophageal cancer can maintain the stability of blood concentration and hemodynamics,shorten the recovery time,and improve the quality of anesthesia recovery and safety.
