Analysis of the risk factors of recurrence after curative resection for gastric adenocarcinoma
10.3760/cma.j.issn.1008-6706.2012.11.013
- VernacularTitle:胃腺癌根治术后复发影响因素分析
- Author:
Guowei LIU
;
Yicai SONG
- Publication Type:Journal Article
- Keywords:
Stomach neplasms;
Recurrence;
Risk factors
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(11):1626-1627
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore prognostic factors associated with early and late recurrences after surgery for patients with gastric adenocarcinoma.Methods 214 patients who underwent curative resection for gastric adenocarcinoma were divided into 2 groups according to recurrence time:an early recurrence group included 143 patients who died within 2 years after surgery,and a late reeurrence group included 71 patients who died more than 2 years after surgery.Indexes such as age,sex,tumor site,tumor size,tumor pathology classification,Borrmann type,TNM staging,lymph node metastasis,operation type and postoperative adjuvant chemotherapy were compared.Results Single factor analysis showed that the tumor diameter,Borrmann type,TNM staging,lymph node metastasis,operation type,adjuvant chemotherapy were asoceiated with postoperative recurrence( test value were 8.32,16.21,24.90,5.22,17.23 and 3.61,respectively;all P ＜ 0.05 ).Multifactor analysis showed that tumor diameter and TNM staging is recurrent independent factors( relative risk were 5.642 and 6.211,respectively ;all P ＜ 0.05 ).Conclusion Tumor size and TNM staging are the most important factors for predicting the timing of recurrence after curative resection for gastric adenocarcinoma.Clinical practice should pay attention to follow up for patients with tumor diameter≥5cm,TNM Ⅲ-Ⅳ stage,especially within two years.
