The expression and clinical significance of MPO in patients with chronic ischemic cerebrovascular disease
10.3760/cma.j.issn.1008-6706.2012.07.014
- VernacularTitle:慢性缺血性脑血管病患者髓过氧化物酶的表达及其意义
- Author:
Lihua MA
;
Wanqing DONG
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Peroxidase;
Ultrasonography;
Carotid artery diseases
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(7):989-990
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the expression and clinical significance of myeloperoxidase (MPO) in patients with chronic ischemic cerebrovascular disease.Methods70 carotid atherosclerotic plaques patients with plasma MPO level in our hospital were measured and taken ultrasound examination at the same time.ResultsThere was no significant difference for those with contrast-enhanced imaging and without increase in the general information (P ＞0.05).The enhanced infarct rate was 80.5％ (33/41).The non-enhanced infarct was 44.8％ (13/29).The carotid plaque ultrasound contrast enhancement in patients with cerebral infarction group was significantly higher than non-enhanced group(P ＜ 0.01 ).In the plasma levels of MPO detection,contrast-enhanced carotid ultrasound group was significantly higher than non-enhanced group( P ＜ 0.01 ).The cerebral infarction patients was significantly higher than non-cerebral infarction group (P ＜ 0.01 ).ConclusionThe atherosclerotic plaque instability in patients with high expression level of MPO was significantly higher,which indicated high level expression of MPO in the diagnosis of chronic cerebrovascular disease had a very important role.Supplemented by the results of ultrasound imaging may had a clear diagnosis.
