Effects of Bupi-Qufeng decoction on serum TIgE and EOS of paitents with atopic dermatitis belonging to spleen deficiency syndrome

VernacularTitle:补脾祛风方对脾虚型特应性皮炎患者血清总免疫球蛋白、嗜酸性粒细胞的影响
Author: Yongping ZHENG ; Gaofei CHEN ; Ling ZHANG ; Haitang WANG ; Xian MENG
Publication Type:Journal Article
Keywords: Atopicdermatitis; Bupi-Qufengdecoction; TIgE; EOS
From: International Journal of Traditional Chinese Medicine 2012;34(5):407-408
CountryChina
Language:Chinese
Abstract: Objective To study the effect of Bupi-Qufeng decoction on total serum IgE (TIgE) and EOS counts of atopic dermatitis (AD).Methods A total of 101 cases were randomly recruited into a treatment group and a control group.During the treatment both groups were give Danggui-Bohe ointment for external use,and based on this,oral Bupi-Qufeng decoction was added in the treatment group and loratadine in the control group.TIgE level and EOS count were detected both before the treatment and four weeks after the treatment.Results TIgE in the treatment group decreased significantly after the treatment (t=8.0063,P＜0.001),the decreased value of which was larger than the control group (t=3.6434,P＜0.001).EOS count in the treatment group also obviously decreased after the treatment (t=3.0314,P＜0.01) ; the decreased value of which was also larger than the control group (t=3.3331,P＜0.01).Conclnsion Bupi-Qufeng decoction could decrease TIgE and EOS level of AD patient,while the therapeutic mechanism needed further research.