Development of urothelial tumors following renal transplantation of 11 cases report

VernacularTitle:肾移植术后并发尿路上皮癌11例临床诊治分析
Author: Wenhui SONG ; Zhijie BAI ; Shijie YAO ; Qian HU ; Haifeng WANG ; Qingtong MA ; Shiqiang YANG ; Hongshun MA
Publication Type:Journal Article
Keywords: Kidney transplantation; Urothelial tumor; Radical operation
From: Clinical Medicine of China 2012;28(5):528-530
CountryChina
Language:Chinese
Abstract: Objective To analyze the incidence and clinical features of urothelial tumors in renal allograft recipients.Methods A retrospective analysis of 1042 patients received renal allografts who had taken immunosuppression for at least six months between 2006 and 2011 in The First Centre Hospital of Tianjin was performed.Results Eleven cases of uroepithelial tumors were diagnosed in the 1042 cases of renal transplantation ( 1.06％ ),of whom 9 cases were noticed by hematuria ( 81.8 ％ ),2 cases ( 18.2％ ) by medical examination.Six patients were diagnosed with multifocal urothelial carcinomas.Surgery was performed on all the patients with renal tumors and followed by chemotherapy or radiotherapy.Conclusion Malignancies in urinary tract after renal transplantation should be bore in mind.Early diagnosis is very important.The treatment options include reducing immunosuppressive agents and removing tumor lesions completely.