The incidence and types of acid-base disorder of critically ill patients in emergency
10.3760/cma.j.issn.1671-0282.2012.05.019
- VernacularTitle:急诊危重病患者酸碱失衡发生率与类型
- Author:
Wenhua GU
;
Zhifang SONG
;
Haojun LI
;
Xiaoli GE
- Publication Type:Journal Article
- Keywords:
Acid-base disorder;
Anion gap;
Potential HCO3 -;
Triple acid-base disorder
- From:
Chinese Journal of Emergency Medicine
2012;21(5):523-526
- CountryChina
- Language:Chinese
-
Abstract:
Objective To reveal the incidence and types of acid-base disorder (ABD) of critically ill patients in emergency.Methods The clinical data of critically ill patients in the resuscitation room were collected prospectively from December 1,2008 to March 31,2009.Both arterial and venous blood samples were collected to detect arterial blood gas analysis and serum electrolytes simultaneously and their ABD were analyzed.Results Of totally 766 cases,the incidence of ABD was 97.3% (745 cases).Among ABD the simple acid-base disorder ( SA BD) was 149 cases ( 20.0% ),dual acid-base disorder (DABD) 525 (70.5% ) and triple acid-base disorder (TABD) 71 (9.5% ).After calculating anion gap (AG),the incidence of TABD increased from 12 to 71 cases and the missed diagnosis rate were 83.1% (59 cases) and after calculating potential HCO3-,the incidence of TABD increased from 8 to 71 cases and the missed diagnosis rate were 88.7% (63 cases).The age of patients with TABD (77.9 ± 10.7 years old) was older ( P < 0.01 ) than that of other two groups of SABD and DABD as well as APACHEⅡ score (25.9 ± 7.1 ) and incidence (22.5% ) of MODS in TABD were higher (P <0.01 ).The mortality of patients with TABD on the first,second,third and seven day were 14.1%,23.9%,26.8% and 38.0% respectively and significantly higher than those in SABD and DABD (P <0.05 or P <0.01 ).Conclusions The incidence of ABD was 97.3%.Calculation of AG and potential HCO3- would help find metabolic acidosis and TABD.The age and APACHEⅡ score were key factors to poor prognosis of patients with TABD.