Relationship between high-density lipoprotein cholesterol and idiopathic pulmonary embolism
10.3760/cma.j.issn.1008-6315.2012.05.012
- VernacularTitle:高密度脂蛋白胆固醇与特发性肺栓塞的关系
- Author:
Yanping ZHOU
;
Jianguo LI
- Publication Type:Journal Article
- Keywords:
Idiopathic pulmonary embolism;
High-density lipoprotein cholesterol;
Total cholesterol;
Low-density lipoprotein cholesterol
- From:
Clinical Medicine of China
2012;28(5):491-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between high-density lipoprotein cholesterol (HDL-C) and idiopathic pulmonary embolism.Methods Clinical data of 34 patients with idiopathic pulmonary embolism from January 2005 to March 2011 were enrolled and healthy people with gender,age and basic diseasematched at the same period were selected as control.The venous blood samples of all the subjects were taken at 7:00 am after 10 hours of fasting and analyzed for total cholesterol (TC),lower-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).Results Compared with healthy people,patients had reduced HDL-C level with a statistical significance ( ( 1.10 ± 0.28 ) mmol/L vs ( 1.49 ± 0.35 ) mmol/L,t =- 5.427,P < 0.05 ).However,no statistically significant differences were found in the levels of TC and LDL- C (P > 0.05 ).HDL-C was correlated with idiopathic pulmonary embolism( r =0.284,P < 0.05 ).Conclusion The levels of HDL-C,but not TC or LDL-C,might be associated with the idiopathic pulmonary embolism.