Analgesic effects of parecoxib sodium after orthopedic subarachnoid block anesthesia
10.3760/cma.j.issn.1001-8050.2012.04.016
- VernacularTitle:帕瑞昔布钠对骨科蛛网膜下腔阻滞麻醉患者术后镇痛的作用
- Author:
Liqiu CHEN
;
Dun DENG
;
Haibo YAN
;
Zhaohui WANG
;
Wenbin ZHANG
;
Weikang ZHANG
;
Limin ZHU
;
Xiaoyu CHEN
;
Peihua YAN
;
Dengfei LI
;
Huafang HUANG
- Publication Type:Journal Article
- Keywords:
Anesthesia and analgesia;
Surgical procedures,operative;
Parecoxib sodium
- From:
Chinese Journal of Trauma
2012;28(4):353-356
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the analgesic effects of parecoxib sodium combined with patient controlled epidural analgesia (PCEA) after orthopedic subarachnoid block anesthesia surgery.Methods Two hundred patients undergone orthopedic subarachnoid block anesthesia surgery were randomly and equally divided into two groups:Group P (treated intravenously with 40 mg parecoxib sodium combined with PCEA at the end of operation) and Group C ( treated intravenously with 0.5 g tramadol combined with PCEA at the end of operation).The visual analog scale (VAS) was performed at 6,12,24,48 and 72 hours postoperatively in two groups.Meanwhile,the press frequency of analgesic pump,effective frequency,side effects and satisfaction degree were recorded. Results The VAS sore of Group P was lower than that of Group C at 6,12,24,48 and 72 hours postoperatively ( P ＜ 0.05 ).Group P showed a less number in aspects of the press frequency of analgesic pump,effective frequency,and side effects at 12 and 24 hours,but a higher satisfactory degree,compared with Group C (P ＜0.05). Conclusion Combined use of parecoxib sodium and PCEA can exert a better analgesic effect and have a low incidence rate of side effects following orthopedic subarachnoid block anesthesia.
