Advances of tumor-associated fibroblasts in carcinogenesis
10.3760/cma.j.issn.1673-422X.2012.03.001
- VernacularTitle:肿瘤相关成纤维细胞与肿瘤相关性研究进展
- Author:
Hongmei WANG
;
Junfa XU
- Publication Type:Journal Article
- Keywords:
Angiogenesis inhibitors;
Tumor-associated fibroblast
- From:
Journal of International Oncology
2012;39(3):163-166
- CountryChina
- Language:Chinese
-
Abstract:
Stromal cell types of the neoplastic microenvironment play important roles in the occurrence and development of tumor.Tumor-associated fibroblasts (TAFs) are the most abundant cells in tumor stroma.They promote the malignant transformation of epithelial cells and other cells through cell-cell communication via various soluble factors.
