Gene targeting diagnosis and treatment in cancer
10.3760/cma.j.issn.1673-422X.2012.03.008
- VernacularTitle:肿瘤的基因靶向检测和治疗
- Author:
Yabing ZHENG
;
Lin WANG
;
Xiaotian CHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Molecular diagnostic techniques;
Antineoplastic agents
- From:
Journal of International Oncology
2012;39(3):186-189
- CountryChina
- Language:Chinese
-
Abstract:
With the development and clinical use of the molecular targeted drugs and individualized treatment,cancer research has been focused on gene targeting diagnosis and treatment.Especially for the epidermal growth factor receptor (EGFR) signaling pathway-related genes,DNA replication-related genes,spindle apparatus format-related genes,cell metabolism-related genes and other molecular targeted detection and treatment,the polymorphism of targeting genes/molecules determines the clinical efficiency of the therapies.