Epidermal growth factor receptor Ⅲ variant and targeted therapy of glioblastoma
10.3760/cma.j.issn.1673-422X.2012.03.012
- VernacularTitle:表皮生长因子受体Ⅲ型突变体与恶性胶质瘤靶向治疗
- Author:
Honglian YAN
;
Longzhen ZHANG
- Publication Type:Journal Article
- Keywords:
Receptor,epidermal growth factor;
Glioma;
Molecular targeted therapy
- From:
Journal of International Oncology
2012;39(3):200-202
- CountryChina
- Language:Chinese
-
Abstract:
Epidermal growth factor receptor Ⅲ variant (EGFRv Ⅲ ) is high expressed in gliomas,which can be used as a target to treat cancer.The therapy methods of glioblastoma targeted for EGFRv Ⅲ include RNA interference,immunotherapy,etc.