Application of epidermal growth factor receptor for radiotherapy of esophageal cancer
10.3760/cma.j.issn.1673-422X.2012.03.018
- VernacularTitle:表皮生长因子受体在食管癌放疗中的应用
- Author:
Heping ZHANG
;
Jiancheng LI
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Receptor,epidermal growth factor;
RNA interference
- From:
Journal of International Oncology
2012;39(3):218-220
- CountryChina
- Language:Chinese
-
Abstract:
Epidermal growth factor receptor ( EGFR) express highly or mutant in esophageal cancer,which causing tumor resistance to radiotherapy and leading to poor radiotherapeutic effects.Treatment with antiEGFR can get radiosensitization.There are three main types of molecular targeted research for EGFR:synthetic monoclonal antibody,small molecule tyrosine kinase inhibitors,and other.strategies modulating EGFR biosynthesis based on RNA interference.
