Mammalian target of rapamycin in gastric cancer
10.3760/cma.j.issn.1673-422X.2012.03.020
- VernacularTitle:哺乳动物雷帕霉素靶蛋白在胃癌的研究进展
- Author:
Xiaoqing CHEN
;
Dongxu WANG
;
Haibin YUAN
- Publication Type:Journal Article
- Keywords:
Gastric Neoplasms;
Mammalian target of rapamycin
- From:
Journal of International Oncology
2012;39(3):222-224
- CountryChina
- Language:Chinese
-
Abstract:
Mammalian target of rapamycin (mTOR) plays an important role in the regulation of cell proliferation,growth,energy metabolism and so on.Clinical research demonstrate that many tumors have its excessive expression, and the mTOR inhibitors rapamycin can resist the development of gastric cancer.Research of mTOR signaling pathway combined with its upstream and downstream has larger value for the early diagnosis,monitoring curative effect and prognosis.
