Thrombosis and prevention after transcatheter occlusion of atrial septal defect
10.3760/cma.j.issn.1673-4408.2012.02.005
- VernacularTitle:房间隔缺损介入封堵术后血栓形成及其防治
- Author:
Qian LIU
- Publication Type:Journal Article
- Keywords:
Atrial septal defect;
Intervention;
Occlusion;
Thrombosis
- From:
International Journal of Pediatrics
2012;39(2):122-124
- CountryChina
- Language:Chinese
-
Abstract:
Transcatheter closure as an alternative to medical surgery has become a preferred therapeutic method to atrial septal defect (ASD).However,thrombopoiesis after occluder implantation has been reported comprehensively and causes a series of serious complications such as cerebral embolism、myocardial infarction,pulmonary embolism and so on.Reasons of device thrombopoiesis are closely associated with atrial fibrillation,persistent atrial septal aneurysm,occluder type,activated coagulation system and occluder endothelialization process.This paper summarizes correlation factors of occluder thrombopoiesis and current related prevention proposal after transcatheter closure of ASD,and provides theoretical and experimental foundation for prevenition of device thrombopoiesis after occluder implantation of ASD.