BRAFV600E gene mutation in papillary thyroid cancer
10.3760/cma.j.issn.1673-422X.2012.03.014
- VernacularTitle:BRAFV600E基因突变与甲状腺乳头状癌
- Author:
Xiaoping JIAO
;
Shengying WANG
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Adenocarcinoma,papillary;
Point mutation
- From:
Journal of International Oncology
2012;39(3):206-208
- CountryChina
- Language:Chinese
-
Abstract:
The BRAFV600E mutation in papillary thyroid carcinoma is the most common genetic event,which is an invasive tumor clinical phenotype and a poor prognosis indicator.The BRAFV600E mutation detection has an important guiding significance for the differential diagnosis of malignant thyroid nodules on preoperative,guiding the surgical resection range of thyroid cancer,judging the patient(s) prognosis and guiding the subsequent treatment of postoperative.