The renal pathological change of 31 Henoch-Sch(o)nlein purpura with normal urine routine

VernacularTitle:31例尿常规正常的过敏性紫癜肾脏病理改变
Author: Yanlan ZHONG ; Xiqiang DANG ; Xiaojie HE ; Zhuwen YI ; Qingnan HE
Publication Type:Journal Article
Keywords: Purpura,Schoenlein-Henoch/UR/PA; Kidney/PA
From: Journal of Chinese Physician 2012;14(3):322-324
CountryChina
Language:Chinese
Abstract: Objective To research Henoch-Schonlein purpura purpura (HSP) and renal pathology in children.Methods 31 hospitalized HSP children that with normal urine routine and accepted renal biopsy in our hospital.Results There were different levels of kidney pathological damage in this group of 31 cases,the results of light microscope were from grade Ⅱ to grade Ⅵ The proportion was grade Ⅱ(35.48％,11 of 31),grade Ⅲ (54.83％,17 of 31),and grade Ⅳ,Ⅴ and Ⅵ (each 1 case of 31,3.23％ ).lmmunofluorescence pathology results were showed as following:merely IgA depositional (48.38％,15 of 31 ),IgA + IgG depositional ( 19.36％,6 of 31 ),IgA + IgM depositional ( 19.36％,6of 31 ),IgA + igG + IgM depositional ( 12.90％,4 of 31 ).Microalbuminuria had been founded in 14 cases,and the microalbuminuria level of 10 cases were higher than normal value( 10 of 14,71.43％ ).Conclusions HSP children had renal pathologic dysfunction,even the urine routine were normal,and the detection of urine microalbumin was a significant marker in the early stage.