Mechanism and prevention of drug-induced renal injury
10.3760/cma.j.issn.1673-4408.2012.02.003
- VernacularTitle:药物性肾损伤发病机制及防治进展
- Author:
Hui ZHANG
- Publication Type:Journal Article
- Keywords:
Drug-induced renal injury;
Acute renal injury;
Pathogenesis;
Prevention;
Treatment
- From:
International Journal of Pediatrics
2012;39(2):115-118
- CountryChina
- Language:Chinese
-
Abstract:
At present drug-induced renal injury is increasing due to a wide variety of drugs and drug abuse problem.Many pathogenesis includes hemodynamic changes,drug damage,inflammation,immunolesion,renal obstruction,rhabdomyolysis,metabolic disorders and so on.Each pathogenesis can influence each other.The complex pathogenesis and non-specific clinical symptoms in early stage lead to missed diagnosis.Early prevention,monitoring and intervention are important in the development of the disease.Supportive therapy is a critical part of the treatment.Some patients with renal impairment have poor prognosis.
