The first organ donation after cardiac death and the first deceased-related renal transplantation in China
10.3760/cma.j.issn.0254-1785.2012.03.004
- VernacularTitle:医院内心脏死亡器官捐献的探索及亲属尸体供肾移植首例报告
- Author:
Junjie MA
;
Zhonghua CHEN
;
Ronghua CAO
;
Haifeng YANG
;
Zehong GUI
;
Zhiqiang CHEN
- Publication Type:Journal Article
- Keywords:
Cardiac death;
Tissue donors;
Kidney transplantation
- From:
Chinese Journal of Organ Transplantation
2012;33(3):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective A new field of organ donation after cardiac death (DCD) has been explored to create additional source to clinic transplantation in China.Methods A 33-years old male patient underwent permanent vegetation state for more than 2 years in ICU after severe head injury.His relatives gave writing consent to donate his organs in order to save his renal failure father and others,if possible,in case of cardiac death.On July 27,2005,the patient's heart arrested.Clinic death was announced.The case was immediately referred to transplant team and Maastricht-V DCD organ procurement was emergently performed and two kidneys were harvested. Estimated warm ischemic time was about 40 min followed by 8 h cold ischemic time.Two adults received the grafts.One of recipients was donor's biological father,namely it was the first case of deceased related renal transplantation (DRRTx) in China.Results Both recipients developed delayed graft function postoperatively and eventually recovered after few weeks.By submission of this article,the DRRTx patient has survived with normal renal function for 77 months (6 years and 5 months).Unfortunately,other patient died from fungus pneumonia after 56 months with normal renal function.Conclusion Non-controlled Maastricht-V DCD could be an additional source to transplantation if prompt reaction could be taken.
