The role of Kisspeptin in sexual development
10.3760/cma.j.issn.1673-4408.2012.02.011
- VernacularTitle:Kisspeptin在性发育中的作用
- Author:
Hong DONG
- Publication Type:Journal Article
- Keywords:
Kisspeptin;
G-protein-coupled receptor 54;
Gonadotrophic hormone;
Hypothalamic pituitarygonad axis
- From:
International Journal of Pediatrics
2012;39(2):142-144
- CountryChina
- Language:Chinese
-
Abstract:
Activation of gonadotrophic hormone neuronstion and downstream reproductive hormones (luteinizing hormone and follicle stimulating hormone) secretion is the key event representing the onset of puberty.Hypothalamic pituitary gonad axis varies among gender,season and the stage of development.A number of hormones are involved in the control of hypothalamic pituitary gonad axis.Kisspeptins are potent secretagogues for gonadotrophic hormone,and the KISS1 gene is a target for regulation by gonadal steroids,metabolic factors,photoperiod,and season.This review focuses on Kisspeptin in the regulation of sexual development.
