Postoperative patient-controlled epidural analgesia with dezocine plus ropivacaine in patients underwent hysterectomy
10.3760/cma.j.issn.1008-6706.2011.21.015
- VernacularTitle:地佐辛复合罗哌卡因用于全子宫切除术后自控硬膜外镇痛的研究
- Author:
Hui LI
;
Keyi WU
;
Jiaxin CHENG
;
Zhixiu YE
- Publication Type:Journal Article
- Keywords:
Analgesia,patient-controlled;
Dezocine;
Morphine;
Ropivacaine;
Anesthesia,epidural;
Hysterec-tomy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(21):2909-2910
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effect and safety of postoperative patient-controlled epidural analgesia with dezocine plus ropivacaine in patients underwent hysterectomy.Methods60 patients,ASA Ⅰ ～ Ⅱ,undergoing hysterectomy operation.were randomly divided into two groups.0.225％ ropivacaine with 0.005％ dezocine ( DR group) or 0.225 ％ ropivacaine with 0.003％ morphine (MR group) were given epidurally after surgery,respectively,with an initial loading dose 5m l,basal dose of 2ml/h,PCA dose of 0.5ml and lockout time of 15 min.Visual analogue score(VAS),Bruggemann comfort scale(BCS),Ramsay sedation score(RSS),PCEA effective compression of the times and adverse effects were determined and compared at 1 h,4h,8h,12h,24h 36h and 48h after operation.PCEA effective compression of the number and incidence of adverse reactions were observed.ResultsThere were no significant differences in VAS,BCS,RSS and PCEA effective compression of the times between two groups( all P ＞ 0.05 ).The percentage of nausea,vomiting and pruritus were significantly lower in group DR than that in group MR( all P ＜0.05).ConclusionPatient-controlled epidural analgesia with dezocine plus ropivacaine in patients underwent hysterectomy had analgesic effect and safety,with less advers eeffects.
