Influence of alcohol overtaking on the expression of Caspase-3 in the mouse seminiferous tubule
10.3760/cma.j.issn.1008-6706.2011.21.017
- VernacularTitle:过量饮酒对鼠生精细胞caspase-3表达的影响
- Author:
Gan LU
;
Xing HANG
- Publication Type:Journal Article
- Keywords:
Testis;
Apoptosis;
Ethanol;
Caspase;
Mice
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(21):2913-2914
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the influence of overtaking of liquor on the expression of caspase-3 in the mouse seminiferous tubule.MethodsAdult mice were given liquor through the stomach.The dose was 4g/kg body weight per day for 5 continuous days.Hybridization in situ was performed for detecting the caspase-3 expression in the mouse seminiferous tubule.ResultsIn the control group,there were few Caspase-3 positive cells in the mouse seminiferous tubule.In the group of five days taking liquor,the caspase-3 positive cell count increased obviously.In the group of ten days taking liquor,the caspase-3 positive cell count was maximum.ConclusionAlcohol could induce the apoptosis of spermatogenic cell.