The preliminary clinical observation of Huganjiexian decoction in the treatment of hepatic cirrhosis
10.3760/cma.j.issn.1673-4246.2012.02.008
- VernacularTitle:护肝解纤汤用于肝硬化的临床观察
- Author:
Jianchang SHU
;
Xionggen ZHOU
;
Xia Lü
;
Haihua ZHOU
;
Zhijian SHAO
;
Guoron YE
;
Haiyan ZHU
;
Qihong YANG
;
Huidong SONG
;
Wenru ZHANG
;
Xiaoyan ZHANG
;
Meiya FU
- Publication Type:Journal Article
- Keywords:
Huganjiexian decoction;
Hepatic cirrhosis;
Liver function
- From:
International Journal of Traditional Chinese Medicine
2012;34(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical therapeutic effects and evaluate the security of Huganjiexian decoction combined with conventional therapy on hepatic cirrhosis.MethodsBy the randomized and prospective study method,34 patients with liver cirrhosis were divided into experimental group and control group.The experimental group was treated with Huganjiexian decoction combined with conventional therapy while the control group was treated with conventional therapy alone.Patients in both groups were treated six months.At the beginning and 6 months after treatment,levels of alanine transaminase (ALT),aspartate transaminase (AST),albumin (ALB),albumin/globulin (A/G),total bilirubin (TBiL),blood urea nitrogen (BUN),serum creatinine (Scr) were determined.Results Levels ofALT、AST、TBiL decreased in both groups after being treated for six months,and the differences of downward trend of the experimental group were more significant than control group (F=36.63,40.31,38.65,P＜0.05).Levels ofALT、AST、TBiL of the experimental group were lower than those of control group significantly (F=8.67,7.62,4.36,P＜0.05 ).The A/G raised in both groups after treatment,and the upward trend of the experimental group was greatly different from that of control group (F=24.10,P＜0.05),the value of A/G of the experimental group was higher than that of control group (F=4.78,P＜0.05).The ALB raised in both groups after treatment,while the upward trend of the experimental group was no different from that of control group (F=0.89,P＞ 0.05).Thevalue of ALB had no significant changes in both groups (F=3.15,P＞0.05).Conclusion Huganjiexian decoction possessed therapeutic effect on hepatic cirrhosis,it had no obvious toxicity and side
