Hedgehog signaling pathway and tumors
10.3760/cma.j.issn.1673-422X.2012.02.007
- VernacularTitle:Hedgehog信号通路与肿瘤的关系
- Author:
Xiangyuan CAO
;
Yaodong ZHAO
;
Meiqing LOU
- Publication Type:Journal Article
- Keywords:
Neoplasms,basal cell;
Medulloblastoma;
Glioma;
Neoplastic stem cells;
Hedgehog signaling pathway
- From:
Journal of International Oncology
2012;39(2):102-104
- CountryChina
- Language:Chinese
-
Abstract:
The Hedgehog (Hh) signaling pathway plays a central important role during embryo development of vertebrate,which participates in regulation of multiple basic life processes including cell proliferation,differentiation and tissue patterning.In normal adult physiology,the pathway is implicated in stem cell maintenance,tissue repair and regeneration.By now,more and more researches have been indicated that the Hh signaling pathway is related to the tumor growth promoting and survival capabilities.
