Pim-3 gene and its related effect
10.3760/cma.j.issn.1673-422X.2012.02.008
- VernacularTitle:pim-3基因及其相关作用
- Author:
Shouliang SUN
;
Jun QIAN
- Publication Type:Journal Article
- Keywords:
Proto-oncogenes;
Apoptosis;
Neoplasms
- From:
Journal of International Oncology
2012;39(2):105-107
- CountryChina
- Language:Chinese
-
Abstract:
Pim-3,a new member of the the proto-oncogene pim family which expresses serine and threonine kinase activity,shows a high similar to pim-1 and pim-2 at the function,structure and sequence.Pim-3 plays an important regulative role in the cell cycle transform,cell apoptosis and occurrence of the malignant tumors by phosphorylating numerous specific substrates.
