Applications of insulin-like growth factor system in colorectal cancer

VernacularTitle:胰岛素样生长因子系统在结直肠癌中的应用
Author: Yongze HU ; Xinlin WU
Publication Type:Journal Article
Keywords: Insulin-like growth factor; Colorectal neoplasms; Diagnosis; Therapy
From: Journal of International Oncology 2012;39(2):146-148
CountryChina
Language:Chinese
Abstract: lnsulin-like growth factor (IGF) system has multiple bioactivities,such as regulating cell proliferation and differentiation,and inhibiting apoptosis and so on.In vivo and in vitro experiments have confirmed that IGF system takes part in the malignant transformation of cells and is related to the growth,invasion and metastasis of toumor.IGF system will be applied to early screening and target therapy for colorectal cancer.