Progress of genome-wide association studies in bladder cancer
10.3760/cma.j.issn.1673-4203.2012.02.010
- VernacularTitle:全基因组关联分析在膀胱癌研究中的进展
- Author:
Qingfeng HU
;
Zhicheng MA
;
Guowei XIA
- Publication Type:Journal Article
- Keywords:
Genome- wide association study;
Bladder cancer;
Genes;
Polymorphism
- From:
International Journal of Surgery
2012;39(2):104-107
- CountryChina
- Language:Chinese
-
Abstract:
Genome-wide association studies use high-throughput genotyping technologies to scan thousands of nucleotides of the entire human genome to investigate the relation of clinical conditions and measurable phenotypes.Bladder cancer is the result of the interaction between genetic variants and environmental factors.Many progresses have been acquired from genome-wide association studies.New genetic regions have been discovered to provide us new strategies for the etiology investigation of bladder cancer.