Granzyme B, B-cell lymphoma/leukemia-2 gene and BH3-interacting domain death agonist in cell apoptais
10.3760/cma.j.issn.1673-4203.2012.02.012
- VernacularTitle:颗粒酶B与B细胞淋巴瘤/白血病-2基因、Bid在细胞凋亡中的研究进展
- Author:
Lei REN
;
Yejiang ZHOU
- Publication Type:Journal Article
- Keywords:
Granzyme B;
B-cell lymphoma/leukemia-2;
BH3-interacting domain death agonis;
Cell apoptosis
- From:
International Journal of Surgery
2012;39(2):111-114
- CountryChina
- Language:Chinese
-
Abstract:
Granzyme B is an important effect factor of cytotoxic T lymphocytes in the immune killer function,can quickly induce cell apoptosis of the target cell.It is complicated for the reasons and the ways of the occurrence of the cell apoptosis,many genes are involved in gene regulation of cell apoptosis,and the B-cell lymphoma/leukemia-2 gene family members play a crucial role in the process of cell apoptosis.This paper mainly reviews the correlation of GrB and Bcl-2,Bid with cell apoptosis.
