Amplified in breast cancer 1 in tumorigenesis
10.3760/cma.j.issn.1673-422X.2012.02.006
- VernacularTitle:乳腺癌扩增基因1与肿瘤
- Author:
Xiao WU
;
Chaoqun HONG
;
Mingyao WU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Receptors,steroid;
Transcription factors
- From:
Journal of International Oncology
2012;39(2):99-101
- CountryChina
- Language:Chinese
-
Abstract:
Amplified in breast cancer 1 ( AIB1 ) plays an important role in the process of gene expression and regulation by combining with nuclear receptor.Aberrant expression of AIB1 has been detected in different types of caners,such as breast cancer,endometrial carcinoma,prostate cancer,esophageal squamous cell carcinoma,colorectal carcinoma,etc.The study of the potential role of AIB1 in the pathogenesis and prognosis will improve our general acknowledge of carcinogenesis.AIB1 may become a new prognostic marker as well as a new therapeutic target.
